标题：Antibiotic resistomes in water supply reservoirs sediments of central China: main biotic drivers and distribution pattern
作者：Kai Zhang, Kuangjia Li, Rui Xin, Ya Han, Ziwei Guo, Wei Zou, Wei Wei, Xiangchao Cui, Zhongshuai Zhang & Ying Zhang
来源出版物：Environmental Science and Pollution Research, 2022年
DOI：10.1007/s11356-021-18095-w出版年: 2022
文献类型：Article
语种：英文
摘要：Water supply reservoirs form one of the critical drinking water resources. Their water quality directly affects human health. However, reservoir sediments have not received adequate attention in antibiotic resistance genes (ARGs) dissemination, though they reflect long-term ARGs contamination of water supply reservoirs. Moreover, the physicochemical parameters in water supply reservoir sediments are generally better than those in the other media. Thus, the main ARGs biotic drivers of the media would demonstrate their unique characteristics. In this study, sediment samples were collected from 10 water supply reservoirs in central China, and the antibiotic resistomes were determined with the metagenomic method. As revealed from the results, 174 ARGs (18 ARG types) were detected in the reservoir sediment. Besides, multidrug-, sulfonamide-, and vancomycin-ARGs were the dominant ARGs in the sediment samples. The macrolide-resistant Microcystis was prevalent (100% detection frequency with 0.35% average percentage) in reservoir sediments and posed potential risks to human health. Furthermore, the results of the Mantel test and VPA demonstrated that mobile genetic elements (MGEs) were the more essential biotic drivers in ARG contents of reservoir sediments rather than the bacteria community.
影响因子：4.306
论文连接：https://link.springer.com/article/10.1007/s11356-021-18095-w